Huimin Hu Selected Research

Cathepsin A

12/2021	AAV-mediated gene therapy for galactosialidosis: A long-term safety and efficacy study.
3/2021	Galactosialidosis: preclinical enzyme replacement therapy in a mouse model of the disease, a proof of concept.
2/2012	Preclinical dose-finding study with a liver-tropic, recombinant AAV-2/8 vector in the mouse model of galactosialidosis.

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Huimin Hu Research Topics

Disease

29	Neoplasms (Cancer) 10/2021 - 12/2010
21	Glioma (Gliomas) 03/2021 - 01/2015
5	Lysosomal Storage Diseases (Lysosomal Storage Disease) 03/2021 - 04/2002
5	Infections 01/2021 - 01/2018
4	Inflammation (Inflammations) 11/2020 - 11/2016
3	Neuraminidase deficiency with beta-galactosidase deficiency 12/2021 - 02/2012
3	Pain (Aches) 10/2021 - 10/2019
3	Mucolipidoses (Sialidosis) 01/2019 - 02/2010
3	Body Weight (Weight, Body) 11/2016 - 02/2010
3	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2016 - 12/2010
2	Neoplasm Metastasis (Metastasis) 10/2021 - 01/2019
2	Margins of Excision 01/2021 - 02/2015
2	Disease Progression 01/2020 - 01/2016
2	Brain Neoplasms (Brain Tumor) 12/2019 - 01/2015
2	Wounds and Injuries (Trauma) 02/2019 - 05/2016
2	Carcinogenesis 01/2017 - 03/2015
2	Glioblastoma (Glioblastoma Multiforme) 02/2015 - 01/2014
2	Chronic Renal Insufficiency 05/2011 - 02/2010
2	Proteinuria 05/2011 - 02/2010
2	Fibrosis (Cirrhosis) 05/2011 - 02/2010
1	Right Ventricular Dysfunction 04/2022
1	Pulmonary Hypertension 04/2022
1	Brain Ischemia (Cerebral Ischemia) 04/2022
1	Ischemic Stroke 04/2022
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/2022
1	Hemorrhagic Disorders (Hemorrhagic Diathesis) 03/2022
1	Osteoarthritis 03/2022
1	Congenital Abnormalities (Deformity) 03/2021
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2021
1	Amnesia (Dissociative Amnesia) 11/2020
1	Scoliosis 01/2020
1	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 01/2020
1	Kyphosis 01/2020

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2010
7	Messenger RNA (mRNA)IBA 11/2019 - 12/2014
5	Biological ProductsIBA 01/2021 - 09/2018
5	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2015
5	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 12/2019 - 01/2015
4	5'-deoxy-5'-phosphonomethyladenosine phosphateIBA 12/2021 - 02/2012
3	MicroRNAs (MicroRNA)IBA 04/2022 - 12/2017
3	Cathepsin AIBA 12/2021 - 02/2012
3	LigandsIBA 01/2021 - 03/2015
3	Phosphotransferases (Kinase)IBA 01/2021 - 03/2015
3	EnzymesIBA 11/2020 - 04/2002
3	Biomarkers (Surrogate Marker)IBA 07/2020 - 12/2014
3	Neuraminidase (Sialidase)IBA 01/2019 - 02/2010
2	Indicators and Reagents (Reagents)IBA 01/2021 - 01/2018
2	CateninsIBA 01/2021 - 12/2010
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2019 - 03/2015
2	ErbB Receptors (EGF Receptor)IBA 12/2019 - 04/2015
2	Small Interfering RNA (siRNA)IBA 11/2019 - 12/2014
2	HomocysteineIBA 02/2019 - 05/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2019
2	Immune Checkpoint InhibitorsIBA 09/2018 - 01/2017
2	NitrogenIBA 11/2016 - 05/2011
2	Urea (Carbamide)FDA LinkGeneric 11/2016 - 05/2011
2	CytokinesIBA 01/2015 - 01/2014
2	Serum AlbuminIBA 05/2011 - 02/2010
2	Dietary ProteinsIBA 05/2011 - 02/2010
1	Oxygen (Dioxygen)IBA 04/2022
1	Glucose (Dextrose)FDA LinkGeneric 04/2022
1	A73025IBA 03/2022
1	PlacebosIBA 10/2021
1	GalactosidasesIBA 03/2021
1	Pharmaceutical PreparationsIBA 03/2021
1	Sermorelin (Sermorelin Acetate)FDA Link 03/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021
1	Vincristine (Oncovin)FDA LinkGeneric 01/2021
1	Carboplatin (JM8)FDA LinkGeneric 01/2021
1	Member 14 Tumor Necrosis Factor ReceptorsIBA 01/2021
1	WastewaterIBA 01/2021
1	pirarubicinIBA 01/2021
1	Ifosfamide FDA LinkGeneric 01/2021
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2021
1	Etoposide (VP 16)FDA LinkGeneric 01/2021
1	AerosolsIBA 01/2021
1	B7-H1 AntigenIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Extracellular Matrix ProteinsIBA 12/2020
1	Epidermal Growth Factor (EGF)IBA 12/2020
1	fibulinIBA 12/2020
1	Scopolamine (Hyoscine)FDA Link 11/2020
1	Metalloproteases (Metalloproteinases)IBA 11/2020
1	p38 Mitogen-Activated Protein KinasesIBA 11/2020
1	ImmunosorbentsIBA 11/2020
1	Aggrecans (Aggrecan)IBA 11/2020
1	Adenosine Triphosphate (ATP)IBA 07/2020
1	ElementsIBA 07/2020
1	Dental Implants (Dental Implant)IBA 01/2020
1	Antiviral Agents (Antivirals)IBA 01/2020

Therapy/Procedure

8	Therapeutics 01/2020 - 02/2010
6	Drug Therapy (Chemotherapy) 10/2021 - 01/2009
4	Immunotherapy 01/2021 - 01/2017
1	Metastasectomy 10/2021
1	Enzyme Replacement Therapy 03/2021
1	Bathroom Equipment 01/2021
1	Electroacupuncture 11/2020
1	Radiotherapy 01/2020